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N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane. Deuterium substitution has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium-labeled isotopologue of N-nitroso-3-azabicyclo[3.3.0]octane provided as a reference material for analytical and research applications. It is supplied as a solid for use as an internal standard in mass spectrometry and isotopic labeling studies; not for human or veterinary use.
Deuterium-labeled internal standard for mass spectrometry.
Suitable for quantitative and qualitative analytical methods.
Provided with batch-specific certificate of analysis.
Stable solid form suitable for recommended long-term storage.
Intended for research use only.
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An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
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Nikkomycin Z is a nucleoside peptide and an orally active antifungal agent. It inhibits chitin synthesis by acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. Nikkomycin Z exhibits antifungal activity.
Inhibits the growth and biofilm formation of *Candida albicans* and *Candida parapsilosis*.
Shows better efficacy when used in combination with echinocandins.
Reduces fungal burden in a murine model of *Histoplasma capsulatum* infection.
Solid appearance.
White to off-white color.
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UCSF924 is a selective dopamine D4 receptor (DRD4) partial agonist chemical probe with nanomolar potency (EC50 = 4.2 nM) and exceptional selectivity against other GPCRs. It is supplied as a white to off-white solid with high purity for use in receptor pharmacology and neuropsychiatric research.
Selective DRD4 partial agonist with EC50 = 4.2 nM.
High selectivity against more than 320 non-olfactory GPCRs.
High purity: 99.5%.
White to off-white solid suitable for laboratory use.
Appropriate for cell-based assays and receptor pharmacology studies.
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Creatine Kinase (CPK/CK), Bovine Heart is a biological material or organic compound intended for use in life science research. It is available in various quantities, including 1 KU, 5 KU, and 10 KU.
Suitable for life science research applications.
Available in multiple unit sizes for flexibility.
Product ships at room temperature within the continental US.
Comprehensive documentation including data sheet, sds, coa, and handling instructions is available.
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1-Methylguanidine monohydrochloride is provided as a white to off-white solid. It has been tested and complies with the given specifications. This product is intended for research use only and has not been fully validated for medical applications.
White to off-white solid appearance
Tested and complies with specifications
Storage at 4°C, sealed, away from moisture
In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
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Creatine (Standard) is an analytical standard of Creatine, an endogenous amino acid derivative crucial for cellular energy in muscle and brain. It is designed for research and analytical applications, serving as a reference in various assays.
Used in qualitative research experiments.
Used in quantitative research experiments.
Used in methodological research experiments.
Applicable in HPLC.
Applicable in GC.
Applicable in MS.
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11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It is suitable for the research of podocyte and diabetic nephropathy.
Significantly reduces NFAT2 expression in high glucose-treated podocytes
Attenuates high glucose-induced filtration barrier dysfunction of podocytes
Abrogates increased urinary albumin excretion rates
Attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement
Partially restores podocyte number
Inhibits NFAT2 activation and uPAR expression in glomerular podocytes
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